The plot follows a team of researchers, led by Dr. Elena Torres (Ana de Armas), who embark on a dangerous expedition to uncover the secrets of a newly discovered species of giant anaconda. Rumored to be larger, faster, and more intelligent than its predecessors, this serpent has earned the title “The Apex Predator” of the jungle. As the team ventures deeper into uncharted territory, they soon realize that they are not just studying the anaconda—it’s hunting them.
Alongside Dr. Torres is a rugged survivalist, Jake Reed (Chris Hemsworth), who is hired to guide the team through the treacherous terrain. The dynamic between the cautious scientist and the instinct-driven adventurer creates a compelling tension as they face not only the deadly serpent but also internal conflicts that threaten their survival.